Recombinant Human TPH2 Protein, His-tagged

• Cat.No.: TPH2-342H
• Product Overview: Recombinant Human TPH2 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
• Source: E. coli
• Tag: His
• Form: Supplied as a 0.2 µM filtered solution of PBS, pH 7.4
• Molecular Mass: 58.8kD
• AA Sequence: MNHKVHHHHHHMQPAMMMFSSKYWA RRGFSLDSAVPEEHQLLGSSTASTF LKLNKPNSGKNDDKGNKGSSKREAA TESGKTAVVFSLKNEVGGLVKALRL FQEKRVNMVHIESRKSRRRSSEVEI FVDCECGKTEFNELIQLLKFQTTIV TLNPPENIWTEEEELEDVPWFPRKI SELDKCSHRVLMYGSELDADHPGFK DNVYRQRRKYFVDVAMGYKYGQPIP RVEYTEEETKTWGVVFRELSKLYPT HACRE
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining

Gene Information

• Gene Name: TPH2 tryptophan hydroxylase 2 [ Homo sapiens ]
• Official Symbol: TPH2
• Synonyms: TPH2; tryptophan hydroxylase 2; tryptophan 5-hydroxylase 2; FLJ37295; NTPH; tryptophan 5-monooxygenase 2; neuronal tryptophan hydroxylase; ADHD7; MGC138871; MGC138872
• Gene ID: 121278
• mRNA Refseq: NM_173353
• Protein Refseq: NP_775489
• MIM: 607478
• UniProt ID: Q8IWU9