Recombinant Human TPH2 Protein, His-tagged

• Cat.No.: TPH2-470H
• Product Overview: Recombinant Human TPH2 Protein (Met1-Leu175) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.7 kDa
  Accurate Molecular Mass: 24 kDa
• Protein length: Met1-Leu175
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: TPH2 tryptophan hydroxylase 2 [ Homo sapiens (human) ]
• Official Symbol: TPH2
• Synonyms: TPH2; tryptophan hydroxylase 2; tryptophan 5-hydroxylase 2; FLJ37295; NTPH; tryptophan 5-monooxygenase 2; neuronal tryptophan hydroxylase; ADHD7; MGC138871; MGC138872
• Gene ID: 121278
• mRNA Refseq: NM_173353
• Protein Refseq: NP_775489
• MIM: 607478
• UniProt ID: Q8IWU9