| Cat.No.: | TPH2-2449H |
| Product Overview: | Recombinant Human TPH2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
| Description: | This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. |
| Source: | HEK293 |
| Species: | Human |
| Tag : | MYC/DDK |
| Form: | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass: | 55.9 kDa |
| Purity: | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration: | >50 ug/mL as determined by microplate BCA method |
| Gene Name: | TPH2 tryptophan hydroxylase 2 [ Homo sapiens ] |
| Official Symbol: | TPH2 |
| Synonyms: | ADHD7; NTPH |
| Gene ID: | 121278 |
| mRNA Refseq: | NM_173353 |
| Protein Refseq: | NP_775489 |
| MIM: | 607478 |
| UniProt ID: | Q8IWU9 |
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