Recombinant Human TPH2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TPH2 Protein, Myc/DDK-tagged, C13 and N15-labeled

TPH2 Related Products

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Cat.No. : TPH2-2024H
Product Overview : TPH2 MS Standard C13 and N15-labeled recombinant protein (NP_775489) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 56.1 kDa
AA Sequence : MQPAMMMFSS KYWARRGFSL DSAVPEEHQL LGSSTLNKPN SGKNDDKGNK GSSKREAATE SGKTAVVFSL KNEVGGLVKA LRLFQEKRVN MVHIESRKSR RRSSEVEIFV DCECGKTEFN ELIQLLKFQT TIVTLNPPEN IWTEEEELED VPWFPRKISE LDKCSHRVLM YGSELDADHP GFKDNVYRQR RKYFVDVAMG YKYGQPIPRV EYTEEETKTW GVVFRELSKL YPTHACREYL KNFPLLTKYC GYREDNVPQL EDVSMFLKER SGFTVRPVAG YLSPRDFLAG LAYRVFHCTQ YIRHGSDPLY TPEPDTCHEL LGHVPLLADP KFAQFSQEIG LASLGASDED VQKLATCYFF TIEFGLCKQE GQLRAYGAGL LSSIGELKHA LSDKACVKAF DPKTTCLQEC LITTFQEAYF VSESFEEAKE KMRDFAKSIT RPFSVYFNPY TQSIEILKDT RSIENVVQDL RSDLNTVCDA LNKMNQYLGI TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TPH2 tryptophan hydroxylase 2 [ Homo sapiens (human) ]
Official Symbol : TPH2
Synonyms : TPH2; tryptophan hydroxylase 2; tryptophan 5-hydroxylase 2; FLJ37295; NTPH; tryptophan 5-monooxygenase 2; neuronal tryptophan hydroxylase; ADHD7; MGC138871; MGC138872;
Gene ID : 121278
mRNA Refseq : NM_173353
Protein Refseq : NP_775489
MIM : 607478
UniProt ID : Q8IWU9

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