Recombinant Human TPM2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TPM2-6005H
• Product Overview: TPM2 MS Standard C13 and N15-labeled recombinant protein (NP_003280) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 32.7 kDa
• AA Sequence: MDAIKKKMQMLKLDKENAIDRAEQA EADKKQAEDRCKQLEEEQQALQKKL KGTEDEVEKYSESVKEAQEKLEQAE KKATDAEADVASLNRRIQLVEEELD RAQERLATALQKLEEAEKAADESER GMKVIENRAMKDEEKMELQEMQLKE AKHIAEDSDRKYEEVARKLVILEGE LERSEERAEVAESKCGDLEEELKIV TNNLKSLEAQADKYSTKEDKYEEEI KLLEEKLKEAETRAEFAERSVAKLE KTIDDLEDEVYAQKMKYKAISEELD NALNDITSLTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TPM2 tropomyosin 2 [ Homo sapiens (human) ]
• Official Symbol: TPM2
• Synonyms: TPM2; tropomyosin 2 (beta); AMCD1, arthrogryposis multiplex congenital, distal, type 1; tropomyosin beta chain; DA1; tropomyosin-2; DA2B; NEM4; TMSB; AMCD1
• Gene ID: 7169
• mRNA Refseq: NM_003289
• Protein Refseq: NP_003280
• MIM: 190990
• UniProt ID: P07951