"TRIB2" Related Products

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Recombinant Human TRIB2 Protein, MYC/DDK-tagged

Cat.No. : TRIB2-2622H
Product Overview : Recombinant Human TRIB2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 38.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TRIB2 tribbles homolog 2 (Drosophila) [ Homo sapiens ]
Official Symbol : TRIB2
Synonyms : C5FW; GS3955; TRB2
Gene ID : 28951
mRNA Refseq : NM_021643
Protein Refseq : NP_067675
MIM : 609462
UniProt ID : Q92519

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