Active Recombinant Human TRIM37 Protein, GST-tagged

• Cat.No.: TRIM37-640H
• Product Overview: Recombinant Human TRIM37 fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: TRIM37 or tripartite motif containing 37 is a member of the tripartite motif (TRIM) family whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in TRIM37 are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
• Bio-activity: 16 nmol/min/mg
• Molecular Mass: 140 kDa
• Purity: >80%
• Applications: Ubiquitin Enzyme Assay, Western Blot
• Stability: 1 year at - 70 centigrade from the date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ml

Gene Information

• Gene Name: TRIM37 tripartite motif containing 37 [ Homo sapiens ]
• Official Symbol: TRIM37
• Synonyms: TRIM37; tripartite motif containing 37; MUL, tripartite motif containing 37; E3 ubiquitin-protein ligase TRIM37; KIAA0898; POB1; RING B box coiled coil protein; TEF3; mulibrey nanism protein; RING-B-box-coiled-coil protein; tripartite motif-containing 37; tripartite motif-containing protein 37; MUL
• Gene ID: 4591
• mRNA Refseq: NM_001005207
• Protein Refseq: NP_001005207
• MIM: 605073
• UniProt ID: O94972