Recombinant Human TRIP13 protein(1-432aa), His-tagged

• Cat.No.: TRIP13-3022H
• Product Overview: Recombinant Human TRIP13 protein(Q15645)(1-432aa), fused with N-terminal His tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: N-His
• Protein length: 1-432aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 54.6 kDa
• AASequence: MDEAVGDLKQALPCVAESPTVHVEV HQRGSSTAKKEDINLSVRKLLNRHN IVFGDYTWTEFDEPFLTRNVQSVSI IDTELKVKDSQPIDLSACTVALHIF QLNEDGPSSENLEEETENIIAANHW VLPAAEFHGLWDSLVYDVEVKSHLL DYVMTTLLFSDKNVNSNLITWNRVV LLHGPPGTGKTSLCKALAQKLTIRL SSRYRYGQLIEINSHSLFSKWFSES GKLVTKMFQKIQDLIDDKDALVFVL IDEVESLTAARNACRAGTEPSDAIR VVNAVLTQIDQIKRHSNVVILTTSN ITEKIDVAFVDRADIKQYIGPPSAA AIFKIYLSCLEELMKCQIIYPRQQL LTLRELEMIGFIENNVSKLSLLLND ISRKSEGLSGRVLRKLPFLAHALYV QAPTVTIEGFLQALSLAVDKQFEER KKLAAYI
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: TRIP13 thyroid hormone receptor interactor 13 [ Homo sapiens ]
• Official Symbol: TRIP13
• Synonyms: TRIP13; thyroid hormone receptor interactor 13; pachytene checkpoint protein 2 homolog; 16E1BP; thyroid receptor interacting protein 13; 16E1-BP; TRIP-13; TR-interacting protein 13; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; thyroid receptor-interacting protein 13; human papillomavirus type 16 E1 protein-binding protein
• Gene ID: 9319
• mRNA Refseq: NM_001166260
• Protein Refseq: NP_001159732
• MIM: 604507
• UniProt ID: Q15645

Reviews

10/27/2018

Dependable for data accuracy. Aids research productivity.

08/01/2017

Precision in analysis. Supports our research consistently.

07/17/2017

Efficient and timely service. Critical for research progress.

Q&As

What role does TRIP13 play in DNA repair mechanisms?

TRIP13 plays a role in DNA repair, contributing to genomic stability and integrity.

What is the impact of altered TRIP13 activity on cancer development?

Altered TRIP13 activity is linked with cancer progression due to its role in cell cycle regulation.

What is the primary role of TRIP13 in cell cycle regulation?

TRIP13 is crucial for the regulation of the cell cycle, particularly in the transition between different phases.

What potential therapeutic applications arise from targeting TRIP13 in cancer therapy?

Targeting TRIP13 could provide a novel approach in cancer treatment, focusing on its role in cell cycle regulation.

How do genetic variations in TRIP13 affect cellular division and stability?

Mutations in TRIP13 can lead to errors in cell division and increased genomic instability.

How does TRIP13 contribute to chromosome segregation during mitosis?

It assists in proper chromosome segregation, ensuring accurate cell division during mitosis.

How does TRIP13 interact with other proteins in cell cycle and DNA repair pathways?

TRIP13 works with other proteins to coordinate cell cycle progression and DNA repair processes.