| Description : |
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
68.7 kDa |
| AA Sequence : |
MSENLDNEGPKPMESCGQESSSALS CPTVSVPPAAPAALEEVEKEGAGAA TGPGPQPGLYSYIRDDLFTSEIFKL ELQNVPRHASFSDVRRFLGRFGLQP HKTKLFGQPPCAFVTFRSAAERDKA LRVLHGALWKGRPLSVRLARPKADP MARRRRQEGESEPPVTRVADVVTPL WTVPYAEQLERKQLECEQVLQKLAK EIGSTNRALLPWLLEQRHKHNKACC PLEGVRPSPQQTEYRNKCEFLVGVG VDGEDNTVGCRLGKYKGGTCAVAAP FDTVHIPEATKQVVKAFQEFIRSTP YSAYDPETYTGHWKQLTVRTSRRHQ AMAIAYFHPQKLSPEELAELKTSLA QHFTAGPGRASGVTCLYFVEEGQRK TPSQEGLPLEHVAGDRCIHEDLLGL TFRISPHAFFQVNTPAAEVLYTVIQ DWAQLDAGSMVLDVCCGTGTIGLAL ARKVKRVIGVELCPEAVEDARVNAQ DNELSNVEFHCGRAEDLVPTLVSRL ASQHLVAILDPPRAGLHSKVILAIR RAKNLRRLLYVSCNPRAAMGNFVDL CRAPSNRVKGIPFRPVKAVAVDLFP QTPHCEMLILFERVEHPNGTGVLGP HSPPAQPTPGPPDNTLQETGTFPSS TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
