"TRPV6" Related Products

Recombinant Human TRPV6 Protein, His-tagged

Cat.No.: TRPV6-349H
Product Overview: Recombinant Human TRPV6(Met578~Ile725) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
Source: E. coli
Species: Human
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 21.2kDa
Protein length: Met578~Ile725
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: TRPV6 transient receptor potential cation channel, subfamily V, member 6 [ Homo sapiens ]
Official Symbol: TRPV6
Synonyms: TRPV6; transient receptor potential cation channel, subfamily V, member 6; ECAC2, epithelial calcium channel 2; transient receptor potential cation channel subfamily V member 6; CaT1; caT-L; calcium channel CaT1; calcium transport protein 1; epithelial calcium channel 2; Alu-binding protein with zinc finger domain; epithelial apical membrane calcium transporter/channel CaT1; CAT1; CATL; ZFAB; ECAC2; ABP/ZF; LP6728; HSA277909;
Gene ID: 55503
mRNA Refseq: NM_018646
Protein Refseq: NP_061116
MIM: 606680
UniProt ID: Q9H1D0

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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