Recombinant Human TSEN2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TSEN2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : TSEN2-3157H
Product Overview : TSEN2 MS Standard C13 and N15-labeled recombinant protein (NP_001138864) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 53.2 kDa
AA Sequence : MAEAVFHAPK RKRRVYETYE SPLPIPFGQD HGPLKEFKIF RAEMINNNVI VRNAEDIEQL YGKGYFGKGI LSRSRPSFTI SDPKLVAKWK DMKTNMPIIT SKRYQHSVEW AAELMRRQGQ DESTVRRILK DYTKPLEHPP VKRNEEAQVH DKLNSGMVSN MEGTAGGERP SVVNGDSGKS GGVGDPREPL GCLQEGSGCH PTTESFEKSV REDASPLPHV CCCKQDALIL QRGLHHEDGS QHIGLLHPGD RGPDHEYVLV EEAECAMSER EAAPNEELVQ RNRLICRRNP YRIFEYLQLS LEEAFFLVYA LGCLSIYYEK EPLTIVKLWK AFTVVQPTFR TTYMAYHYFR SKGWVPKVGL KYGTDLLLYR KGPPFYHASY SVIIELVDDH FEGSLRRPLS WKSLAALSRV SVNVSKELML CYLIKPSTMT DKEMESPECM KRIKVQEVIL SRWVSSRERS DQDDLTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TSEN2 tRNA splicing endonuclease subunit 2 [ Homo sapiens (human) ]
Official Symbol : TSEN2
Synonyms : TSEN2; tRNA splicing endonuclease 2 homolog (S. cerevisiae); tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae); tRNA-splicing endonuclease subunit Sen2; MGC2776; SEN2; SEN2L; hsSen2; tRNA-intron endonuclease Sen2; PCH2B; MGC4440;
Gene ID : 80746
mRNA Refseq : NM_001145392
Protein Refseq : NP_001138864
MIM : 608753
UniProt ID : Q8NCE0

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