Recombinant Human TSG101 Protein (Pro144-Leu373), His tagged

• Cat.No.: TSG101-3422H
• Product Overview: Recombinant human TSG101 (Pro144-Leu373) protein fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Pro144-Leu373
• Description: Tumor susceptibility gene 11 (TSG11) is a multi-functional gene involved in cell growth and proliferation in vertebrates. The tumor susceptibility gene 11 (TSG11) regulates AR expression level via the endosome/lysosome degradation pathway, that the interaction of the AR and TSG11 leads to androgen receptor (AR) recruitment to TSG11-containing cytoplasmic vesicles and induces AR-attenuated expression through the late endosome/lysosome degradation pathway. TSG11 elicits an array of cellular functions, including promoting cytokinesis, cell cycle progression and proliferation, as well as facilitating endosomal trafficking and viral budding.
• Molecular Mass: 26.12 kDa
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: TSG101 tumor susceptibility gene 101 [ Homo sapiens (human) ]
• Official Symbol: TSG101
• Synonyms: TSG101; tumor susceptibility gene 101; TSG10, tumor susceptibility gene 10; tumor susceptibility gene 101 protein; VPS23; tumor susceptibility protein; ESCRT-I complex subunit TSG101; TSG10
• Gene ID: 7251
• mRNA Refseq: NM_006292
• Protein Refseq: NP_006283
• MIM: 601387
• UniProt ID: Q99816