Recombinant Human TSPO, T7-tagged

• Cat.No.: TSPO1-2961H
• Product Overview: Recombinant Human TSPO (1-102 aa) is expressed inE.Coliwith a T7 tag at N-terminus.

Specification

• Cat. No.: TSPO1-2961H
• Description: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Source: E.Coli.
• MW: 16107 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
• Application: MS. SDS.

Gene Information

• Gene Name: TSPO translocator protein (18kDa) [ Homo sapiens ]
• Synonyms: TSPO; translocator protein (18kDa); OTTHUMP00000198251; benzodiazepine peripheral binding site; mitochondrial benzodiazepine receptor; peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor; translocator protein; DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18
• Gene ID: 706
• mRNA Refseq: NM_000714
• Protein Refseq: NP_000705
• MIM: 109610
• UniProt ID: P30536
• Chromosome Location: 22q13.31
• Pathway: Neuroactive ligand-receptor interaction
• Function: benzodiazepine receptor activity; cholesterol binding; receptor activity