Recombinant Human TSPYL5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TSPYL5-3394H
• Product Overview: TSPYL5 MS Standard C13 and N15-labeled recombinant protein (NP_277047) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45 kDa
• AA Sequence: MSGRSRGRKSSRAKNRGKGRAKARV RPAPDDAPRDPDPSQYQSLGEDTQA AQVQAGAGWGGLEAAASAQLLRLGE EAACRLPLDCGLALRARAAGDHGQA AARPGPGKAASLSERLAADTVFVGT AGTVGRPKNAPRVGNRRGPAGKKAP ETCSTAGRGPQVIAGGRQKKGAAGE NTSVSAGEEKKEERDAGSGPPATEG SMDTLENVQLKLENMNAQADRAYLR LSRKFGQLRLQHLERRNHLIQNIPG FWGQAFQNHPQLASFLNSQEKEVLS YLNSLEVEELGLARLGYKIKFYFDR NPYFQNKVLIKEYGCGPSGQVVSRS TPIQWLPGHDLQSLSQGNPENNRSF FGWFSNHSSIESDKVVEIINEELWP NPLQFYLLSEGARVEKGKEKEGRQG PGKQPMETTQPGVSQSNTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TSPYL5 TSPY-like 5 [ Homo sapiens (human) ]
• Official Symbol: TSPYL5
• Synonyms: TSPYL5; TSPY-like 5; testis-specific Y-encoded-like protein 5; KIAA1750; TSPY-like protein 5
• Gene ID: 85453
• mRNA Refseq: NM_033512
• Protein Refseq: NP_277047
• MIM: 614721
• UniProt ID: Q86VY4