Recombinant Human TTR (L55P) Protein (Full Length)

• Cat.No.: TTR-04H
• Product Overview: Recombinant Human TTR (L55P) Protein (Full Length) without tag was expressed inn E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: Full Length
• Description: This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome.
• Purity: > 95% pure using SDS-PAGE analysis.
• Applications: WB, SDS-PAGE, In vivo assay, In vitro assay
• Notes: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Storage: At -80 centigrade.
• Storage Buffer: PBS pH 7.4
• Shipping: Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

Gene Information

• Gene Name: TTR transthyretin [ Homo sapiens (human) ]
• Official Symbol: TTR
• Synonyms: TTR; transthyretin; CTS; TTN; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651; transthyretin; epididymis luminal protein 111; prealbumin, amyloidosis type I; thyroxine-binding prealbumin
• Gene ID: 7276
• mRNA Refseq: NM_000371
• Protein Refseq: NP_000362
• MIM: 176300
• UniProt ID: P02766