Recombinant Human TTR Protein, His-tagged
Cat.No. : | TTR-291H |
Product Overview : | Recombinant Human TTR fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | THis gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in tHis gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. |
Source : | E. coli |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigradeentigradeentigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Molecular Mass : | 15.9 |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | TTR transthyretin [ Homo sapiens ] |
Official Symbol : | TTR |
Synonyms : | TTR; transthyretin; PALB, prealbumin, amyloidosis type I; HsT2651; ATTR; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin, amyloidosis type I; CTS; CTS1; PALB; TBPA; |
Gene ID : | 7276 |
mRNA Refseq : | NM_000371 |
Protein Refseq : | NP_000362 |
MIM : | 176300 |
UniProt ID : | P02766 |
Products Types
◆ Recombinant Protein | ||
TTR-1059C | Recombinant Cynomolgus TTR Protein, His-tagged | +Inquiry |
TTR-2530H | Recombinant Human TTR protein(31-130 aa), C-His-tagged | +Inquiry |
TTR-9747M | Recombinant Mouse TTR Protein, His (Fc)-Avi-tagged | +Inquiry |
TTR-072H | Recombinant Human TTR Protein | +Inquiry |
Ttr-6725M | Recombinant Mouse Ttr Protein, Myc/DDK-tagged | +Inquiry |
◆ Native Protein | ||
TTR-31108TH | Native Human TTR | +Inquiry |
TTR-155B | Native Bovine Prealbumin protein | +Inquiry |
TTR-706H | Native Human Transthyretin | +Inquiry |
◆ Lysates | ||
TTR-2149HCL | Recombinant Human TTR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionTTR is involved in the transport of thyroxine and retinol and plays a role in processes such as protein degradation.
RAGE proteins interact with TTR proteins and are involved in the regulation of TRR expression.
TTR proteins are highly conserved and are found in several vertebrates, such as humans, rats, sheep, and chickens.
TTR is mainly synthesized in the liver.
TTR is associated with a variety of diseases including amyloidosis TTR (ATTR), dementia (AD) and neurological damage.
Customer Reviews (3)
Write a reviewTimely delivery, so I got the desired experimental results in the shortest possible time.
I have a dedicated staff member who contacts me and keeps me informed on the progress of custom protein production.
The purchased product information is in line with the advertising campaign and is conducive to obtaining accurate experimental results.
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