Recombinant Human Tubulin Folding Cofactor A
Cat.No. : | TBCA-6925H |
Product Overview : | Recombinant human TBCA protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 12.8 kDa. |
- Specification
- Gene Information
- Related Products
Description : | TBCA is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. |
Source : | E. coli |
Species : | Human |
Tag : | N/A |
Form : | Liquid. In 20 mM Tris-HCl buffer pH 7.5 containing 1 mM DTT, 10% glycerol. |
Molecular Mass : | 12.8 kDa (108aa), confirmed by MALDI-TOF. |
Protein length : | 1-108aa |
AA Sequence : | MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | TBCA tubulin folding cofactor A [ Homo sapiens ] |
Official Symbol : | TBCA |
Synonyms : | TBCA; tubulin folding cofactor A; tubulin specific chaperone a; tubulin-specific chaperone A; CFA; chaperonin cofactor A; TCP1-chaperonin cofactor A; tubulin-folding cofactor A; |
Gene ID : | 6902 |
mRNA Refseq : | NM_004607 |
Protein Refseq : | NP_004598 |
MIM : | 610058 |
UniProt ID : | O75347 |
Chromosome Location : | 5q14.1 |
Pathway : | Metabolism of proteins, organism-specific biosystem; Post-chaperonin tubulin folding pathway, organism-specific biosystem; Protein folding, organism-specific biosystem; |
Function : | chaperone binding; unfolded protein binding; |
Products Types
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TBCA-5625R | Recombinant Rat TBCA Protein, His (Fc)-Avi-tagged | +Inquiry |
TBCA-29833TH | Recombinant Human TBCA protein(Met1-Ala108) | +Inquiry |
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◆ Lysates | ||
TBCA-1220HCL | Recombinant Human TBCA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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