Recombinant Human TXNDC Protein, GST-tagged

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Recombinant Human TXNDC Protein, GST-tagged

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Cat.No. : TXNDC5-1110H
Product Overview : Human TXNDC5 full-length ORF ( AAH52310.1, 1 a.a. - 360 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 66.8 kDa
AA sequence : MTQSVDSNRG NRNEKRCGHC QRLQPTWNDL GDKYNSMEDA KVYVAKVDCT AHSDVCSAQG VRGYPTLKLF KPGQEAVKYQ GPRDFQTLEN WMLQTLNEEP VTPEPEVEPP SAPELKQGLY ELSASNFELH VAQGDHFIKF FAPWCGHCKA LAPTWEQLAL GLEHSETVKI GKVDCTQHYE LCSGNQVRGY PTLLWFRDGK KVDQYKGKRD LESLREYVES QLQRTETGAT ETVTPSEAPV LAAEPEADKG TVLALTENNF DDTIAEGITF IKFYAPWCGH CKTLAPTWEE LSKKEFPGLA GVKIAEVDCT AERNICSKYS VRGYPTLLLF RGGKKVSEHS GGRDLDSLHR FVLSQAKDEL
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : TXNDC5 thioredoxin domain containing 5 [ Homo sapiens (human) ]
Official Symbol : TXNDC5
Synonyms : TXNDC5; thioredoxin domain containing 5 (endoplasmic reticulum); thioredoxin domain containing 5; thioredoxin domain-containing protein 5; EndoPDI; ERp46; FLJ21353; FLJ90810; Hcc 2; MGC3178; PDIA15; protein disulfide isomerase family A; member 15; ER protein 46; thioredoxin related protein; thioredoxin-like protein p46; endoplasmic reticulum protein ERp46; endothelial protein disulphide isomerase; endoplasmic reticulum resident protein 46; protein disulfide isomerase family A, member 15; ERP46; HCC-2; STRF8; UNQ364; ENDOPDI; FLJ21789
Gene ID : 81567
mRNA Refseq : BC052310.1
Protein Refseq : AAH52310.1
MIM : 616412
UniProt ID : Q8NBS9
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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