Description : |
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
55.1 kDa |
AA Sequence : |
MASKKLGADFHGTFSYLDDVPFKTG DKFKTPAKVGLPIGFSLPDCLQVVR EVQYDFSLEKKTIEWAEEIKKIEEA EREAECKIAEAEAKVNSKSGPEGDS KMSFSKTHSTATMPPPINPILASLQ HNSILTPTRVSSSATKQKVLSPPHI KADFNLADFECEEDPFDNLELKTID EKEELRNILVGTTGPIMAQLLDNNL PRGGSGSVLQDEEVLASLERATLDF KPLHKPNGFITLPQLGNCEKMSLSS KVSLPPIPAVSNIKSLSFPKLDSDD SNQKTAKLASTFHSTSCLRNGTFQN SLKPSTQSSASELNGHHTLGLSALN LDSGTEMPALTSSQMPSLSVLSVCT EESSPPNTGPTVTPPNFSVSQVPNM PSCPQAYSELQMLSPSERQCVETVV NMGYSYECVLRAMKKKGENIEQILD YLFAHGQLCEKGFDPLLVEEALEMH QCSEEKMMEFLQLMSKFKEMGFELK DIKEVLLLHNNDQDNALEDLMARAG ASTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |