Cat.No.:	UBE2D3-2004H
Product Overview:	Recombinant Human UBE2D3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Met147) of human UBE2D3 (Accession #NP_003331.1) fused with a 6×His tag at the C-terminus.
Description:	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
Source:	E. coli
Species:	Human
Tag :	His
Form:	Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol.
Protein length:	Met1-Met147
Endotoxin:	< 1.0 EU per μg of the protein as determined by the LAL method.
Purity:	> 90% as determined by SDS-PAGE
Stability:	Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage:	Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.

Gene Name:	UBE2D3 ubiquitin conjugating enzyme E2 D3 [ Homo sapiens (human) ]
Official Symbol:	UBE2D3
Synonyms:	E2(17)KB3;UBC4/5;UBCH5C
Gene ID:	7323
mRNA Refseq:	NM_181893
Protein Refseq:	NP_003331.1
MIM:	602963
UniProt ID:	P61077

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