Recombinant Human UBE3A Protein UBE3A-315H

Recombinant Human UBE3A Protein

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Recombinant Human UBE3A Protein

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Cat.No. : UBE3A-315H
Product Overview : Recombinant Human UBE3A Protein is produced by Bacteria expression system.
Description : UbE3A (also called E6AP) is a 100 kDa HECT (homologous to E6AP carboxyl terminus) domain ubiquitin ligase containing two E2 binding sites for UbcH7 and UbcH8. UbE3A was found to bind to the human papillomavirus (HPV) oncoprotein E6 and mediate ubiquitination of p53. A frameshift mutation in the UbE3A gene leads to loss of function and causes Angelman Syndrome.
Source : Bacteria
Species : Human
Form : 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Molecular Mass : 100.7 kDa
Purity : > 90 % by SDS-PAGE
Storage : Store at -80 centigrade; avoid multiple freeze-thaw cycles.
Gene Name : UBE3A ubiquitin protein ligase E3A ( Homo sapiens )
Official Symbol : UBE3A
Synonyms : AS; ANCR; E6-AP; E6AP; HPVE6A; EPVE6AP
Gene ID : 7337
mRNA Refseq : NM_000462.3
Protein Refseq : NP_000453
MIM : 601623
UniProt ID : Q05086

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