Recombinant Human UBQLN1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human UBQLN1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : UBQLN1-4186H
Product Overview : UBQLN1 MS Standard C13 and N15-labeled recombinant protein (NP_444295) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 59.2 kDa
AA Sequence : MAESGESGGP PGSQDSAAGA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT NTAGSNVTTS STPNSNSTSG SATSNPFGLG GLGGLAGLSS LGLNTTNFSE LQSQMQRQLL SNPEMMVQIM ENPFVQSMLS NPDLMRQLIM ANPQMQQLIQ RNPEISHMLN NPDIMRQTLE LARNPAMMQE MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMLSAAQEQ FGGNPFASLV SNTSSGEGSQ PSRTENRDPL PNPWAPQTSQ SSSASSGTAS TVGGTTGSTA SGTSGQSTTA PNLVPGVGAS MFNTPGMQSL LQQITENPQL MQNMLSAPYM RSMMQSLSQN PDLAAQMQNP DTLSAMSNPR AMQALLQIQQ GLQTLATEAP GLIPGFTPGL GALGSTGGSS GTNGSNATPS ENTSPTAGTT EPGHQQFIQQ MLQALAGVNP QLQNPEVRFQ QQLEQLSAMG FLNREANLQA LIATGGDINA AIERLLGSQP STRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : UBQLN1 ubiquilin 1 [ Homo sapiens (human) ]
Official Symbol : UBQLN1
Synonyms : UBQLN1; ubiquilin 1; ubiquilin-1; DA41; DSK2; PLIC 1; XDRP1; hPLIC-1; protein linking IAP with cytoskeleton 1; UBQN; PLIC-1; FLJ90054;
Gene ID : 29979
mRNA Refseq : NM_053067
Protein Refseq : NP_444295
MIM : 605046
UniProt ID : Q9UMX0

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