Recombinant Human UBR7 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UBR7-4043H
• Product Overview: UBR7 MS Standard C13 and N15-labeled recombinant protein (NP_786924) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.8 kDa
• AA Sequence: MAGAEGAAGRQSELEPVVSLVDVLE EDEELENEACAVLGGSDSEKCSYSQ GSVKRQALYACSTCTPEGEEPAGIC LACSYECHGSHKLFELYTKRNFRCD CGNSKFKNLECKLLPDKAKVNSGNK YNDNFFGLYCICKRPYPDPEDEIPD EMIQCVVCEDWFHGRHLGAIPPESG DFQEMVCQACMKRCSFLWAYAAQLA VTKISTEDDGLVRNIDGIGDQEVIK PENGEHQDSTLKEDVPEQGKDDVRE VKVEQNSEPCAGSSSESDLQTVFKN ESLNAESKSGCKLQELKAKQLIKKD TATYWPLNWRSKLCTCQDCMKMYGD LDVLFLTDEYDTVLAYENKGKIAQA TDRSDPLMDTLSSMNRVQQVELICE YNDLKTELKDYLKRFADEGTVVKRE DIQQFFEEFQSKKRRRVDGMQYYCS TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UBR7 ubiquitin protein ligase E3 component n-recognin 7 [ Homo sapiens (human) ]
• Official Symbol: UBR7
• Synonyms: UBR7; ubiquitin protein ligase E3 component n-recognin 7 (putative); C14orf130, chromosome 14 open reading frame 130; putative E3 ubiquitin-protein ligase UBR7; N-recognin-7; C14orf130; MGC9518; FLJ10483
• Gene ID: 55148
• mRNA Refseq: NM_175748
• Protein Refseq: NP_786924
• MIM: 613816
• UniProt ID: Q8N806