Recombinant Human UBTF Protein (1-670 aa), His-SUMO-tagged

• Cat.No.: UBTF-2505H
• Product Overview: Recombinant Human UBTF Protein (1-670 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial.

Specification

• Description: Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 95.2 kDa
• Protein length: 1-670 aa
• AA Sequence: MNGEADCPTDLEMAAPKGQDRWSQE DMLTLLECMKNNLPSNDSSKFKTTE SHMDWEKVAFKDFSGDMCKLKWVEI SNEVRKFRTLTELILDAQEHVKNPY KGKKLKKHPDFPKKPLTPYFRFFME KRAKYAKLHPEMSNLDLTKILSKKY KELPEKKKMKYIQDFQREKQEFERN LARFREDHPDLIQNAKKSDIPEKPK TPQQLWYTHEKKVYLKVRPDATTKE VKDSLGKQWSQLSDKKRLKWIHKAL EQRKEYEEIMRDYIQKHPELNISEE GITKSTLTKAERQLKDKFDGRPTKP PPNSYSLYCAELMANMKDVPSTERM VLCSQQWKLLSQKEKDAYHKKCDQK KKDYEVELLRFLESLPEEEQQRVLG EEKMLNINKKQATSPASKKPAQEGG KGGSEKPKRPVSAMFIFSEEKRRQL QEERPELSESELTRLLARMWNDLSE KKKAKYKAREAALKAQSERKPGGER EERGKLPESPKRAEEIWQQSVIGDY LARFKNDRVKALKAMEMTWNNMEKK EKLMWIKKAAEDQKRYERELSEMRA PPAATNSSKKMKFQGEPKKPPMNGY QKFSQELLSNGELNHLPLKERMVEI GSRWQRISQSQKEHYKKLAEEQQKQ YKVHLDLWVKSLSPQDRAAYKEYIS NKRKSMTKLRGPNPKSSRTT
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: UBTF upstream binding transcription factor, RNA polymerase I [ Homo sapiens ]
• Official Symbol: UBTF
• Synonyms: UBTF; NOR 90; UBF; autoantigen NOR-90; UBF1; UBF-1; NOR-90
• Gene ID: 7343
• mRNA Refseq: NM_001076683
• Protein Refseq: NP_001070151
• MIM: 600673
• UniProt ID: P17480