Recombinant Human UBXN1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UBXN1-994H
• Product Overview: UBXN1 MS Standard C13 and N15-labeled recombinant protein (NP_056937) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.1 kDa
• AA Sequence: MAELTALESLIEMGFPRGRAEKALA LTGNQGIEAAMDWLMEHEDDPDVDE PLETPLGHILGREPTSSEQGGLEGS GSAAGEGKPALSEEERQEQTKRMLE LVAQKQREREEREEREALERERQRR RQGQELSAARQRLQEDEMRRAAEER RREKAEELAARQRVREKIERDKAER AKKYGGSVGSQPPPVAPEPGPVPSS PSQEPPTKREYDQCRIQVRLPDGTS LTQTFRAREQLAAVRLYVELHRGEE LGGGQDPVQLLSGFPRRAFSEADME RPLQELGMAARLETRTRNWGSREAC LGKGGMQREGALTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UBXN1 UBX domain protein 1 [ Homo sapiens (human) ]
• Official Symbol: UBXN1
• Synonyms: UBXN1; UBX domain protein 1; UBX domain-containing protein 1; 2B28; LOC51035; SAKS1; SAPK substrate protein 1; UBXD10; UBA/UBX 33.3 kDa protein
• Gene ID: 51035
• mRNA Refseq: NM_015853
• Protein Refseq: NP_056937
• MIM: 616378
• UniProt ID: Q04323