Recombinant Human UCHL1 protein, T7/His-tagged
Cat.No. : | UCHL1-227H |
Product Overview : | Recombinant human UCHL1 cDNA (1 – 220 aa, derived from BC005117) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Sucrose. |
AA Sequence : | MASMTGGQQMGRGHHHHHHENLYFQ GGEFQLKPMEINPEMLNKVLSRLGV AGQWRFVDVLGLEEESLGSVPAPAC ALLLLFPLTAQHENFRKKQIEELKG QEVSPKVYFMKQTIGNSCGTIGLIH AVANNQDKLGFEDGSVLKQFLSETE KMSPEDRAKCFEKNEAIQAAHDAVA QEGQCRVDDKVNFHFILFNNVDGHL YELDGRMPFPVNHGASSEDTLLKDA AKVCREFTEREQGEVRFSAVALC |
Purity : | >90% by SDS-PAGE |
Storage : | Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days. |
Gene Name : | UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) [ Homo sapiens ] |
Official Symbol : | UCHL1 |
Synonyms : | UCHL1; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); PARK5; ubiquitin carboxyl-terminal hydrolase isozyme L1; PGP9.5; Uch L1; ubiquitin thioesterase L1; neuron cytoplasmic protein 9.5; ubiquitin C-terminal hydrolase; PGP95; Uch-L1; PGP 9.5; |
Gene ID : | 7345 |
mRNA Refseq : | NM_004181 |
Protein Refseq : | NP_004172 |
MIM : | 191342 |
UniProt ID : | P09936 |
Chromosome Location : | 4p13 |
Pathway : | Alpha-synuclein signaling, organism-specific biosystem; Parkinsons disease, organism-specific biosystem; |
Function : | alpha-2A adrenergic receptor binding; cysteine-type endopeptidase activity; ligase activity; omega peptidase activity; peptidase activity; protein binding; ubiquitin binding; ubiquitin thiolesterase activity; |
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◆ Lysates | ||
UCHL1-535HCL | Recombinant Human UCHL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionEarly research suggests that changes in UCHL1 levels may be detected in the early stages of some neurodegenerative diseases, but more studies are needed for validation.
While UCHL1 is primarily associated with neurological functions, it also has roles in non-neuronal tissues, including certain types of cancer cells.
Challenges include the need for standardized assays, variations in UCHL1 levels among individuals, and the influence of other factors on its expression.
Yes, elevated or decreased levels of UCHL1 in cerebrospinal fluid or blood may serve as potential biomarkers for certain neurological disorders.
UCHL1 dysfunction has been implicated in conditions such as certain cancers and ischemic stroke.
Customer Reviews (3)
Write a reviewWhether it is regarding experimental design, optimization of protocols, or troubleshooting issues, their expertise and prompt customer service help researchers overcome challenges efficiently.
They provide comprehensive technical assistance and guidance throughout the entire research process.
Heir responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.
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