Recombinant Human UGCG protein, MYC/DDK-tagged

• Cat.No.: UGCG-3580H
• Product Overview: Recombinant Human UGCG fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: UGCG UDP-glucose ceramide glucosyltransferase [ Homo sapiens ]
• Official Symbol: UGCG
• Synonyms: UGCG; UDP-glucose ceramide glucosyltransferase; ceramide glucosyltransferase; GCS; glucosylceramide synthase; GLCT-1; UDP-glucose:N-acylsphingosine D-glucosyltransferase; GLCT1
• Gene ID: 7357
• mRNA Refseq: NM_003358
• Protein Refseq: NP_003349
• MIM: 602874
• UniProt ID: Q16739
• Chromosome Location: 9q31
• Pathway: Glycosphingolipid metabolism, organism-specific biosystem; IL2 signaling events mediated by PI3K, organism-specific biosystem; Lactosylceramide biosynthesis, organism-specific biosystem; Lactosylceramide biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem
• Function: ceramide glucosyltransferase activity; transferase activity, transferring glycosyl groups