| Description : |
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
142.3 kDa |
| AA Sequence : |
MENFILYEEIGRGSKTVVYKGRRKG TINFVAILCTDKCKRPEITNWVRLT REIKHKNIVTFHEWYETSNHLWLVV ELCTGGSLKTVIAQDENLPEDVVRE FGIDLISGLHHLHKLGILFCDISPR KILLEGPGTLKFSNFCLAKVEGENL EEFFALVAAEEGGGDNGENVLKKSM KSRVKGSPVYTAPEVVRGADFSISS DLWSLGCLLYEMFSGKPPFFSESIS ELTEKILCEDPLPPIPKDSSRPKAS SDFINLLDGLLQRDPQKRLTWTRLL QHSFWKKAFAGADQESSVEDLSLSR NTMECSGPQDSKELLQNSQSRQAKG HKSGQPLGHSFRLENPTEFRPKSTL EGQLNESMFLLSSRPTPRTSTAVEV SPGEDMTHCSPQKTSPLTKITSGHL SQQDLESQMRELIYTDSDLVVTPII DNPKIMKQPPVKFDAKILHLPTYSV DKLLFLKDQDWNDFLQQVCSQIDST EKSMGASRAKLNLLCYLCVVAGHQE VATRLLHSPLFQLLIQHLRIAPNWD IRAKVAHVIGLLASHTAELQENTPV VEAIVLLTELIRENFRNSKLKQCLL PTLGELIYLVATQEEKKKNPRECWA VPLAAYTVLMRCLREGEERVVNHMA AKIIENVCTTFSAQSQGFITGEIGP ILWYLFRHSTADSLRITAVSALCRI TRHSPTAFQNVIEKVGLNSVINSLA SAICKVQQYMLTLFAAMLSCGIHLQ RLIQEKGFVSTIIRLLDSPSTCIRA KAFLVLLYILIYNREMLLLSCQARL VMYIERDSRKTTPGKEQQSGNEYLS KCLDLLICHIVQELPRILGDILNSL ANVSGRKHPSTVQVKQLKLCLPLMP VVLHLVTSQVFRPQVVTEEFLFSYG TILSHIKSVDSGETNIDGAIGLTAS EEFIKITLSAFEAIIQYPILLKDYR STVVDYILPPLVSLVQSQNVEWRLF SLRLLSETTSLLVNQEFGDGKEKAS VDSDSNLLALIRDVLLPQYEHILLE PDPVPAYALKLLVAMTEHNPTFTRL VEESKLIPLIFEVTLEHQESILGNT MQSVIALLSNLVACKDSNMELLYEQ GLVSHICNLLTETATLCLDVDNKNN NEMAAPLLFSLLDILHSMLTYTSGI VRLALQAQKSGSGEDPQAAEDLLLL NRPLTDLISLLIPLLPNEDPEIFDV SSKCLSILVQLYGGENPDSLSPENV EIFAHLLTSKEDPKEQKLLLRILRR MITSNEKHLESLKNAGSLLRALERL APGSGSFADSAVAPLALEILQAVGH TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
