Recombinant Human USP51 Protein (R363-Q706), His/Flag tagged

• Cat.No.: USP51-1220H
• Product Overview: Recombinant Human 8His-Flag-TEV-USP51(R363-Q706) Protein was expressed in Insect cell.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag&His
• Protein Length: R363-Q706
• Description: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: USP51 ubiquitin specific peptidase 51 [ Homo sapiens (human) ]
• Official Symbol: USP51
• Synonyms: USP51; ubiquitin specific peptidase 51; ubiquitin carboxyl-terminal hydrolase 51; deubiquitinating enzyme 51; ubiquitin thioesterase 51; ubiquitin thiolesterase 51; ubiquitin-specific-processing protease 51; EC 3.4.19.12
• Gene ID: 158880
• mRNA Refseq: NM_201286
• Protein Refseq: NP_958443
• UniProt ID: Q70EK9