Recombinant Human V-set and immunoglobulin domain containing 4 Protein, His&Flag tagged

• Cat.No.: VSIG4-212H
• Product Overview: Recombinant human VSIG4 protein (Q9Y279-1) (Arg 20-Pro 283) with both His, Flag tag at the C-terminus was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: 20-283aa
• Description: This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
• Tag: C-His&Flag
• Molecular Mass: 31.9 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: VSIG4 V-set and immunoglobulin domain containing 4 [ Homo sapiens (human) ]
• Official Symbol: VSIG4
• Synonyms: VSIG4; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; Z39IG; protein Z39Ig; Ig superfamily protein; complement receptor of the immunoglobulin superfamily; CRIg
• Gene ID: 11326
• mRNA Refseq: NM_001100431
• Protein Refseq: NP_001093901
• MIM: 300353
• UniProt ID: Q9Y279