Recombinant Human Vascular Cell Adhesion Molecule 1, His-tagged

Cat.No. : VCAM1-6796H
Product Overview : Recombinant humanVCAM1 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.
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Cat. No. : VCAM1-6796H
Description : VCAM1 is a member ofthe Ig superfamily and is a cell surface sialoglycoprotein expressed bycytokine-activated endothelium. This type I membrane protein mediatesleukocyte-endothelial cell adhesion and signal transduction, and may play arole in the development of artherosclerosis and rheumatoid arthritis
Form : Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 10% glycerol
Molecular Weight : 76 kDa (695aa)
Purity : > 80% by SDS -PAGE
Concentration : 0.25 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MFKIETTPES RYLAQIGDSV SLTCSTTGCE SPFFSWRTQI DSPLNGKVTN EGTTSTLTMNPVSFGNEHSY LCTATCESRK LEKGIQVEIY SFPKDPEIHL SGPLEAGKPI TVKCSVADVY PFDRLEIDLLKGDHLMKSQE FLEDADRKSL ETKSLEVTFT PVIEDIGKVL VCRAKLHIDE MDSVPTVRQA VKELQVYISPKNTVISVNPS TKLQEGGSVT MTCSSEGLPA PEIFWSKKLD NGNLQHLSGN ATLTLIAMRM EDSGIYVCEGVNLIGKNRKE VELIVQEKPF TVEISPGPRI AAQIGDSVML TCSVMGCESP SFSWRTQIDS PLSGKVRSEGTNSTLTLSPV SFENEHSYLC TVTCGHKKLE KGIQVELYSF PRDPEIEMSG GLVNGSSVTV SCKVPSVYPLDRLEIELLKG ETILENIEFL EDTDMKSLEN KSLEMTFIPT IEDTGKALVC QAKLHIDDME FEPKQRQSTQTLYVNVAPRD TTVLVSPSSI LEEGSSVNMT CLSQGFPAPK ILWSRQLPNG ELQPLSENAT LTLISTKMEDSGVYLCEGIN QAGRSRKEVE LIIQVTPKDI KLTAFPSESV KEGDTVIISC TCGNVPETWI ILKKKAETGDTVLKSIDGAY TIRKAQLKDA GVYECESKNK VGSQLRSLTL DVQGRENNKD YFSPE
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Cell adhesion molecules (CAMs);Leukocyte transendothelial migration; Signaling in Immune system
SDS-PAGE:
Gene Name : VCAM1 vascular cell adhesionmolecule 1 [ Homo sapiens ]
Official Symbol : VCAM1
Synonyms : VCAM1; CD106; MGC99561; INCAM-100;DKFZp779G2333; vascular cell adhesion molecule 1; CD106 antigen;OTTHUMP00000012650; OTTHUMP00000012651; L1CAM; V-CAM 1
Gene ID : 7412
mRNA Refseq : NM_001078
Protein Refseq : NP_001069
MIM : 192225
UniProt ID : P19320
Chromosome Location : 1p32-p31
Function : integrin binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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