| Description : |
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
81.3 kDa |
| AA Sequence : |
MPGKMVVILGASNILWIMFAASQAF KIETTPESRYLAQIGDSVSLTCSTT GCESPFFSWRTQIDSPLNGKVTNEG TTSTLTMNPVSFGNEHSYLCTATCE SRKLEKGIQVEIYSFPKDPEIHLSG PLEAGKPITVKCSVADVYPFDRLEI DLLKGDHLMKSQEFLEDADRKSLET KSLEVTFTPVIEDIGKVLVCRAKLH IDEMDSVPTVRQAVKELQVYISPKN TVISVNPSTKLQEGGSVTMTCSSEG LPAPEIFWSKKLDNGNLQHLSGNAT LTLIAMRMEDSGIYVCEGVNLIGKN RKEVELIVQEKPFTVEISPGPRIAA QIGDSVMLTCSVMGCESPSFSWRTQ IDSPLSGKVRSEGTNSTLTLSPVSF ENEHSYLCTVTCGHKKLEKGIQVEL YSFPRDPEIEMSGGLVNGSSVTVSC KVPSVYPLDRLEIELLKGETILENI EFLEDTDMKSLENKSLEMTFIPTIE DTGKALVCQAKLHIDDMEFEPKQRQ STQTLYVNVAPRDTTVLVSPSSILE EGSSVNMTCLSQGFPAPKILWSRQL PNGELQPLSENATLTLISTKMEDSG VYLCEGINQAGRSRKEVELIIQVTP KDIKLTAFPSESVKEGDTVIISCTC GNVPETWIILKKKAETGDTVLKSID GAYTIRKAQLKDAGVYECESKNKVG SQLRSLTLDVQGRENNKDYFSPELL VLYFASSLIIPAIGMIIYFARKANM KGSYSLVEAQKSKVTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
