Recombinant Human VDR, His-tagged

• Cat.No.: VDR-3659H
• Product Overview: Recombinant Human VDR protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 128-427aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
• Publications:
  The functional role of the cell adhesion molecule L1 in mitochondrial metabolism and dynamics and the functional consequences of L1´s interaction with nuclear receptors in the murine central nervous system (2017)
  A Fragment of Adhesion Molecule L1 Binds to Nuclear Receptors to Regulate Synaptic Plasticity and Motor Coordination (2018)

Gene Information

• Gene Name: VDR vitamin D (1,25- dihydroxyvitamin D3) receptor [ Homo sapiens ]
• Official Symbol: VDR
• Synonyms: VDR; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D3 receptor; NR1I1; 1,25-dihydroxyvitamin D3 receptor; vitamin D nuclear receptor variant 1; nuclear receptor subfamily 1 group I member 1
• Gene ID: 7421
• mRNA Refseq: NM_000376
• Protein Refseq: NP_000367
• MIM: 601769
• UniProt ID: P11473
• Chromosome Location: 12q12-q14
• Pathway: Direct p53 effectors, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Gene Expression, organism-specific b
• Function: DNA binding; metal ion binding; protein binding; receptor activity; retinoid X receptor binding; sequence-specific DNA binding; contributes_to sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; contributes_to v