Recombinant Human VDR Protein, MYC/DDK-tagged

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Recombinant Human VDR Protein, MYC/DDK-tagged

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Cat.No. : VDR-101H
Product Overview : Recombinant human VDR protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.
Description : This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 48.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : vitamin D receptor [ Homo sapiens ]
Official Symbol : VDR
Synonyms : NR1I1; PPP1R163
Gene ID : 7421
mRNA Refseq : NM_000376.2
Protein Refseq : NP_000367.1
MIM : 601769
UniProt ID : P11473

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