Recombinant Human VEGFA Protein, Fc-tagged
Cat.No. : | VEGFA-35H |
Product Overview : | Recombinant VEGF165-Fc protein contains 403 amino acids which was expressed from vegf165 gene fused with Fc region of human IgG1 at its C-terminus was produced in a mammalian cell line. |
- Specification
- Gene Information
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Source : | Mammalian cell line |
Species : | Human |
Tag : | Fc |
Molecular Mass : | 49KDa |
Purity : | Greater than 95% by SDS-PAGE |
Storage : | Upon reconstitution, the preparation is stable for up to 1 month at 2-8 centigrade. For long term storage, apportion the reconstituted preparation into working aliquots and store at -20 centigrade to -70 centigrade. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.22μm filtered solution at a concentration of 1mg/ml in PBS. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water to a concentration of 1.0 mg/ml. |
Shipping : | The Product is shipped at ambient temperature. |
Gene Name : | VEGFA vascular endothelial growth factor A [ Homo sapiens (human) ] |
Official Symbol : | VEGFA |
Synonyms : | VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor |
Gene ID : | 7422 |
mRNA Refseq : | NM_001025370 |
Protein Refseq : | NP_001020541 |
MIM : | 192240 |
UniProt ID : | P15692 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionStudies have shown that there is an association between the expression level of VEGFA protein and other biomarkers, for example, it can be associated with indicators such as tumor cell differentiation, metastatic capacity, and prognosis.
At present, a variety of drugs have been developed to target the VEGFA protein and its related signaling pathway, including inhibiting its expression and inhibiting its binding to receptors, etc., for the treatment of tumors and other vascular-related diseases.
VEGFA protein plays a key role in tumor angiogenesis, promoting tumor growth and metastasis by stimulating endothelial cell proliferation, migration, and vascular network formation.
The expression of VEGFA protein in different tissues and organs is different, and it is expressed in tumor tissue, cardiovascular system and other tissues and organs, and the expression level may be affected by many factors.
Studies have shown that the expression level of VEGFA protein is related to the degree of malignancy of the tumor, and the high expression of VEGFA protein often indicates that the tumor is more aggressive.
VEGFA protein plays an important role in cardiovascular disease by regulating endothelial cell function, promoting vascular repair and maintaining cardiovascular system homeostasis.
Customer Reviews (2)
Write a reviewVEGFA's catalytic activity is so strong that it can adapt even in the face of complex chemical reactions.
VEGFA they produced was highly active and the experimental effect was obvious.
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