Recombinant Human VEGFD

• Cat.No.: VEGFD-353H

Specification

• Species: Human
• Source: Sf21 Cells
• Tag: Non
• Description: Vascular endothelial growth factor D (VEGF-D) is a potent angiogenic factor that is a member of the VEGF family that activates VEGF receptor-2. VEGF-D is also lymphangiogenic, and promotes metastatic spread of tumor cells via lymphatic vessels. It may be useful in the treatment of breast cancer as a decision-making biomarker for aggressive treatment after operation.
• Molecular Weight: The predicted molecular weight of Recombinant Human VEGF-D is Mr 13 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 20-22 kDa.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: FIGF c-fos induced growth factor (vascular endothelial growth factor D) [ Homo sapiens ]
• Synonyms: FIGF; c-fos induced growth factor (vascular endothelial growth factor D); VEGFD; VEGF-D; vascular endothelial growth factor D; c-fos-induced growth factor; OTTHUMP00000022960
• Gene ID: 2277
• mRNA Refseq: NM_004469
• Protein Refseq: NP_004460
• MIM: 300091
• UniProt ID: O43915
• Chromosome Location: Xp22.31
• Pathway: adder cancer; Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; mTOR signaling pathway; Hemostasis; Signaling byVEGF
• Function: growth factor activity; platelet-derived growth factor receptor binding; protein homodimerization activity; vascular endothelial growth factor receptor 3 binding