Recombinant Human VIPAS39 Protein (1-493 aa), His-SUMO-tagged

• Cat.No.: VIPAS39-1150H
• Product Overview: Recombinant Human VIPAS39 Protein (1-493 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length.

Specification

• Description: May play a role in vesicular trafficking during spermatogenesis . Plays a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes. May play a role in epithelial polarization through stabilization of apical mbrane protein content, possibly via the RAB11A-dependent apical recycling pathway. Also involved in direct or indirect transcriptional regulation of E-cadherin.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 73.0 kDa
• Protein length: 1-493 aa
• AA Sequence: MNRTKGDEEEYWNSSKFKAFTFDDE DDELSQLKESKRAVNSLRDFVDDDD DDDLERVSWSGEPVGSISWSIRETA GNSGSTHEGREQLKSRNSFSSYAQL PKPTSTYSLSSFFRGRTRPGSFQSL SDALSDTPAKSYAPELGRPKGEYRD YSNDWSPSDTVRRLRKGKVCSLERF RSLQDKLQLLEEAVSMHDGNVITAV LIFLKRTLSKEILFRELEVRQVALR HLIHFLKEIGDQKLLLDLFRFLDRT EELALSHYREHLNIQDPDKRKEFLK TCVGLPFSAEDSAHIQDHYTLLERQ IIIEANDRHLESAGQTEIFRKHPRK ASILNMPLVTTLFYSCFYHYTEAEG TFSSPVNLKKTFKIPDKQYVLTALA ARAKLRAWNDVDALFTTKNWLGYTK KRAPIGFHRVVEILHKNNAPVQILQ EYVNLVEDVDTKLNLATKFKCHDVV IDTYRDLKDRQQLLAYRSKVDKGSA EEEKIDALLSSSQIRWKN
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog [ Homo sapiens (human) ]
• Official Symbol: VIPAS39
• Synonyms: SPE39; VIPAR; SPE-39; VPS16B; hSPE-39; C14orf133
• Gene ID: 63894
• UniProt ID: Q9H9C1