| Description : |
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
83 kDa |
| Protein Length : |
873 |
| AA Sequence : |
MGTSALWALWLLLALCWAPRESGAT GTGRKAKCEPSQFQCTNGRCITLLW KCDGDEDCVDGSDEKNCVKKTCAES DFVCNNGQCVPSRWKCDGDPDCEDG SDESPEQCHMRTCRIHEISCGAHST QCIPVSWRCDGENDCDSGEDEENCG NITCSPDEFTCSSGRCISRNFVCNG QDDCSDGSDELDCAPPTCGAHEFQC STSSCIPISWVCDDDADCSDQSDES LEQCGRQPVIHTKCPASEIQCGSGE CIHKKWRCDGDPDCKDGSDEVNCPS RTCRPDQFECEDGSCIHGSRQCNGI RDCVDGSDEVNCKNVNQCLGPGKFK CRSGECIDISKVCNQEQDCRDWSDE PLKECHINECLVNNGGCSHICKDLV IGYECDCAAGFELIDRKTCGDIDEC QNPGICSQICINLKGGYKCECSRGY QMDLATGVCKAVGKEPSLIFTNRRD IRKIGLERKEYIQLVEQLRNTVALD ADIAAQKLFWADLSQKAIFSASIDD KVGRHVKMIDNVYNPAAIAVDWVYK TIYWTDAASKTISVATLDGTKRKFL FNSDLREPASIAVDPLSGFVYWSDW GEPAKIEKAGMNGFDRRPLVTADIQ WPNGITLDLIKSRLYWLDSKLHMLS SVDLNGQDRRIVLKSLEFLAHPLAL TIFEDRVYWIDGENEAVYGANKFTG SELATLVNNLNDAQDIIVYHELVQP SGKNWCEEDMENGGCEYLCLPAPQI NDHSPKYTCSCPSGYNVEENGRDCQ STATTVTYSETKDTNTTEISATSGL VPGGINVTTAVSEVSVPPKGTSAAW AILPLLLLVMAAVGGYLMWRNWQHK NMKSMNFDNPVYLKTTEEDLSIDIG RHSASVGHTYPAISVVSTDDDLA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
