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Recombinant Human VPS4B Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : VPS4B-5193H
Product Overview : VPS4B MS Standard C13 and N15-labeled recombinant protein (NP_004860) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 49.3 kDa
AA Sequence : MSSTSPNLQKAIDLASKAAQEDKAG NYEEALQLYQHAVQYFLHVVKYEAQ GDKAKQSIRAKCTEYLDRAEKLKEY LKNKEKKAQKPVKEGQPSPADEKGN DSDGEGESDDPEKKKLQNQLQGAIV IERPNVKWSDVAGLEGAKEALKEAV ILPIKFPHLFTGKRTPWRGILLFGP PGTGKSYLAKAVATEANNSTFFSIS SSDLVSKWLGESEKLVKNLFQLARE NKPSIIFIDEIDSLCGSRSENESEA ARRIKTEFLVQMQGVGVDNDGILVL GATNIPWVLDSAIRRRFEKRIYIPL PEPHARAAMFKLHLGTTQNSLTEAD FRELGRKTDGYSGADISIIVRDALM QPVRKVQSATHFKKVRGPSRADPNH LVDDLLTPCSPGDPGAIEMTWMDVP GDKLLEPVVSMSDMLRSLSNTKPTV NEHDLLKLKKFTEDFGQEGTRTRPL EQKLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : VPS4B vacuolar protein sorting 4 homolog B [ Homo sapiens (human) ]
Official Symbol : VPS4B
Synonyms : VPS4B; vacuolar protein sorting 4 homolog B (S. cerevisiae); SKD1, suppressor of K+ transport defect 1, vacuolar protein sorting 4B (yeast); vacuolar protein sorting-associated protein 4B; SKD1B; VPS4 2; cell migration-inducing 1; vacuolar protein sorting 4B; suppressor of K+ transport defect 1; cell migration-inducing gene 1 protein; suppressor of K(+) transport growth defect 1; MIG1; SKD1; VPS4-2;
Gene ID : 9525
mRNA Refseq : NM_004869
Protein Refseq : NP_004860
MIM : 609983
UniProt ID : O75351

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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