| Description : |
The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
125.8 kDa |
| AA Sequence : |
MPATRKPMRYGHTEGHTEVCFDDSG SFIVTCGSDGDVRIWEDLDDDDPKF INVGEKAYSCALKSGKLVTAVSNNT IQVHTFPEGVPDGILTRFTTNANHV VFNGDGTKIAAGSSDFLVKIVDVMD SSQQKTFRGHDAPVLSLSFDPKDIF LASASCDGSVRVWQISDQTCAISWP LLQKCNDVINAKSICRLAWQPKSGK LLAIPVEKSVKLYRRESWSHQFDLS DNFISQTLNIVTWSPCGQYLAAGSI NGLIIVWNVETKDCMERVKHEKGYA ICGLAWHPTCGRISYTDAEGNLGLL ENVCDPSGKTSSSKVSSRVEKDYND LFDGDDMSNAGDFLNDNAVEIPSFS KGIINDDEDDEDLMMASGRPRQRSH ILEDDENSVDISMLKTGSSLLKEEE EDGQEGSIHNLPLVTSQRPFYDGPM PTPRQKPFQSGSTPLHLTHRFMVWN SIGIIRCYNDEQDNAIDVEFHDTSI HHATHLSNTLNYTIADLSHEAILLA CESTDELASKLHCLHFSSWDSSKEW IIDLPQNEDIEAICLGQGWAAAATS ALLLRLFTIGGVQKEVFSLAGPVVS MAGHGEQLFIVYHRGTGFDGDQCLG VQLLELGKKKKQILHGDPLPLTRKS YLAWIGFSAEGTPCYVDSEGIVRML NRGLGNTWTPICNTREHCKGKSDHY WVVGIHENPQQLRCIPCKGSRFPPT LPRPAVAILSFKLPYCQIATEKGQM EEQFWRSVIFHNHLDYLAKNGYEYE ESTKNQATKEQQELLMKMLALSCKL EREFRCVELADLMTQNAVNLAIKYA SRSRKLILAQKLSELAVEKAAELTA TQVEEEEEEEDFRKKLNAGYSNTAT EWSQPRFRNQVEEDAEDSGEADDEE KPEIHKPGQNSFSKSTNSSDVSAKS GAVTFSSQGRVNPFKVSASSKEPAM SMNSARSTNILDNMGKSSKKSTALS RTTNNEKSPIIKPLIPKPKPKQASA ASYFQKRNSQTNKTEEVKEENLKNV LSETPAICPPQNTENQRPKTGFQMW LEENRSNILSDNPDFSDEADIIKEG MIRFRVLSTEERKVWANKAKGETAS EGTEAKKRKRVVDESDETENQEEKA KENLNLSKKQKPLDFSTNQKLSAFA FKQETRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
