Recombinant Human WDR43 Protein, Myc/DDK-tagged, C13 and N15-labeled WDR43-2101H

Recombinant Human WDR43 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human WDR43 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : WDR43-2101H
Product Overview : WDR43 MS Standard C13 and N15-labeled recombinant protein (NP_055946) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 74.7 kDa
AA Sequence : MAAGGGGSCD PLAPAGVPCA FSPHSQAYFA LASTDGHLRV WETANNRLHQ EYVPSAHLSG TCTCLAWAPA RLQAKESPQR KKRKSEAVGM SNQTDLLALG TAVGSILLYS TVKGELHSKL ISGGHDNRVN CIQWHQDSGC LYSCSDDKHI VEWNVQTCKV KCKWKGDNSS VSSLCISPDG KMLLSAGRTI KLWVLETKEV YRHFTGHATP VSSLMFTTIR PPNESQPFDG ITGLYFLSGA VHDRLLNVWQ VRSENKEKSA VMSFTVTDEP VYIDLTLSEN KEEPVKLAVV CRDGQVHLFE HILNGYCKKP LTSNCTIQIA TPGKGKKSTP KPIPILAAGF CSDKMSLLLV YGSWFQPTIE RVALNSREPH MCLVRDISNC WAPKVETAIT KVRTPVMNSE AKVLVPGIPG HHAAIKPAPP QTEQVESKRK SGGNEVSIEE RLGAMDIDTH KKGKEDLQTN SFPVLLTQGL ESNDFEMLNK VLQTRNVNLI KKTVLRMPLH TIIPLLQELT KRLQGHPNSA VLMVQWLKCV LTVHASYLST LPDLVPQLGT LYQLMESRVK TFQKLSHLHG KLILLITQVT ASEKTKGATS PGQKAKLVYE EESSEEESDD EIADKDSEDN WDEDEEESES EKDEDVEEED EDAEGKDEEN GEDRDTASEK ELNGDSDLDP ENESEEETRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : WDR43 WD repeat domain 43 [ Homo sapiens (human) ]
Official Symbol : WDR43
Synonyms : WDR43; WD repeat domain 43; UTP5; NET12; WD repeat-containing protein 43; U3 small nucleolar RNA-associated protein 5 homolog; UTP5, small subunit (SSU) processome component, homolog
Gene ID : 23160
mRNA Refseq : NM_015131
Protein Refseq : NP_055946
MIM : 616195
UniProt ID : Q15061
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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