Recombinant Human WDR43 Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | WDR43-2101H |
Product Overview : | WDR43 MS Standard C13 and N15-labeled recombinant protein (NP_055946) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 74.7 kDa |
AA Sequence : | MAAGGGGSCD PLAPAGVPCA FSPHSQAYFA LASTDGHLRV WETANNRLHQ EYVPSAHLSG TCTCLAWAPA RLQAKESPQR KKRKSEAVGM SNQTDLLALG TAVGSILLYS TVKGELHSKL ISGGHDNRVN CIQWHQDSGC LYSCSDDKHI VEWNVQTCKV KCKWKGDNSS VSSLCISPDG KMLLSAGRTI KLWVLETKEV YRHFTGHATP VSSLMFTTIR PPNESQPFDG ITGLYFLSGA VHDRLLNVWQ VRSENKEKSA VMSFTVTDEP VYIDLTLSEN KEEPVKLAVV CRDGQVHLFE HILNGYCKKP LTSNCTIQIA TPGKGKKSTP KPIPILAAGF CSDKMSLLLV YGSWFQPTIE RVALNSREPH MCLVRDISNC WAPKVETAIT KVRTPVMNSE AKVLVPGIPG HHAAIKPAPP QTEQVESKRK SGGNEVSIEE RLGAMDIDTH KKGKEDLQTN SFPVLLTQGL ESNDFEMLNK VLQTRNVNLI KKTVLRMPLH TIIPLLQELT KRLQGHPNSA VLMVQWLKCV LTVHASYLST LPDLVPQLGT LYQLMESRVK TFQKLSHLHG KLILLITQVT ASEKTKGATS PGQKAKLVYE EESSEEESDD EIADKDSEDN WDEDEEESES EKDEDVEEED EDAEGKDEEN GEDRDTASEK ELNGDSDLDP ENESEEETRT RPLEQKLISE EDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | WDR43 WD repeat domain 43 [ Homo sapiens (human) ] |
Official Symbol : | WDR43 |
Synonyms : | WDR43; WD repeat domain 43; UTP5; NET12; WD repeat-containing protein 43; U3 small nucleolar RNA-associated protein 5 homolog; UTP5, small subunit (SSU) processome component, homolog |
Gene ID : | 23160 |
mRNA Refseq : | NM_015131 |
Protein Refseq : | NP_055946 |
MIM : | 616195 |
UniProt ID : | Q15061 |
◆ Recombinant Protein
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WDR4 WDR5 WDR6 WDR20 WDR61 WDR77 WDR13 WDR36 WDR42A WDR79 WDR41 WDR45L WDR87 WDR88 WDR89 WDR18 WDR70 WDR73 WDR74 WDR75 WDR76 WDR46 WDR49 WDR26 WDR27 WDR3 WDR19 WDR31 WDR33 WDR35 WDR37 WDR44 WDR45 WDR54 WDR59 WDR5B WDR62 WDR65 WDR66 WDR11 WDR12 WDR16 WDR1 WDR78 WDR8 WDR85 WDR86 WDR91 WDR53 WDR92 WDR17 WDR24 WDR25 WDR43 WDR47 WDR48 WDR60 WDR63 WDR64 WDR69 Wdr20a WDR52 WDR81 WDR83OS WDR83 WDR90 WDR93 WDR82 Wdr95 Wdr20b Wdr25l WDR34 Wdr35l Wdr38 Wdr55 Wdr67 Wdr7 Wdr72 Wdr96
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