Recombinant Human WDR54 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: WDR54-3388H
• Product Overview: WDR54 MS Standard C13 and N15-labeled recombinant protein (NP_115494) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.9 kDa
• AA Sequence: MFRWERSIPLRGSAAALCNNLSVLQ LPARNLTYFGVVHGPSAQLLSAAPE GVPLAQRQLHAKEGAGVSPPLITQV HWCVLPFRVLLVLTSHRGIQMYESN GYTMVYWHALDSGDASPVQAVFARG IAASGHFICVGTWSGRVLVFDIPAK GPNIVLSEELAGHQMPITDIATEPA QGQDCVADMVTADDSGLLCVWRSGP EFTLLTRIPGFGVPCPSVQLWQGII AAGYGNGQVHLYEATTGNLHVQINA HARAICALDLASEVGKLLSAGEDTF VHIWKLSRNPESGYIEVEHCHGECV ADTQLCGARFCDSSGNSFAVTGYDL AEIRRFSSVTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: WDR54 WD repeat domain 54 [ Homo sapiens (human) ]
• Official Symbol: WDR54
• Synonyms: WDR54; WD repeat domain 54; WD repeat-containing protein 54; FLJ12953
• Gene ID: 84058
• mRNA Refseq: NM_032118
• Protein Refseq: NP_115494
• UniProt ID: Q9H977