Recombinant Human XAF1 Protein, GST/His-tagged

• Cat.No.: XAF1-225H
• Product Overview: Recombinant human XAF1 protein, fused to GST at N-terminal and His at C-terminal, was expressed in E.coli.

Specification

• Description: This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
• Source: E. coli
• Species: Human
• Tag: GST/His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
• Molecular Mass: 62.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: XIAP associated factor 1 [ Homo sapiens ]
• Official Symbol: XAF1
• Synonyms: BIRC4BP; HSXIAPAF1; XIAPAF1
• Gene ID: 54739
• mRNA Refseq: NM_017523.3
• Protein Refseq: NP_059993.2
• MIM: 606717
• UniProt ID: Q6GPH4