Recombinant Human XRCC3 Protein, His-tagged

• Cat.No.: XRCC3-627H
• Product Overview: Recombinant Human XRCC3, transcript variant 3, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 37.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 [ Homo sapiens ]
• Official Symbol: XRCC3
• Synonyms: XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; DNA repair protein XRCC3; RAD51 like; X-ray repair cross-complementing protein 3; CMM6
• Gene ID: 7517
• mRNA Refseq: NM_001100118
• Protein Refseq: NP_001093588
• MIM: 600675
• UniProt ID: O43542