Recombinant Human XYLT2 Protein (Phe596-Arg865), N-His tagged

• Cat.No.: XYLT2-5467H
• Product Overview: Recombinant human XYLT2 (Phe596-Arg865) fused with the N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Alternatively spliced transcript variants have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 32.53 kDa
• Protein Length: Phe596-Arg865
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: XYLT2 xylosyltransferase 2 [ Homo sapiens (human) ]
• Official Symbol: XYLT2
• Synonyms: XYLT2; xylosyltransferase 2; SOS; XT2; XT-II; PXYLT2; xylT-II; xylosyltransferase 2; UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase; peptide O-xylosyltransferase 1; protein xylosyltransferase 2; xylosyltransferase II; EC 2.4.2.26
• Gene ID: 64132
• mRNA Refseq: NM_022167
• Protein Refseq: NP_071450
• MIM: 608125
• UniProt ID: Q9H1B5