Recombinant Human YWHAE Protein, His-tagged

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Recombinant Human YWHAE Protein, His-tagged

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Cat.No. : YWHAE-150H
Product Overview : Recombinant human YWHAE protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description : This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008].
Source : E. coli
Species : Human
Tag : His
Form : Lyophilized from a 0.2 µM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Molecular Mass : 56 kDa
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Resuspend the protein to the desired concentration in proper buffer.
Gene Name : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon [ Homo sapiens ]
Official Symbol : YWHAE
Synonyms : 14-3-3E; HEL2; KCIP-1; MDCR; MDS
Gene ID : 7351
mRNA Refseq : NM_006761.4
Protein Refseq : NP_006752.1
MIM : 605066
UniProt ID : P62258

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