| Description : |
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
74.1 kDa |
| AA Sequence : |
MDLTKMGMIQLQNPSHPTGLLCKAN QMRLAGTLCDVVIMVDSQEFHAHRT VLACTSKMFEILFHRNSQHYTLDFL SPKTFQQILEYAYTATLQAKAEDLD DLLYAAEILEIEYLEEQCLKMLETI QASDDNDTEATMADGGAEEEEDRKA RYLKNIFISKHSSEESGYASVAGQS LPGPMVDQSPSVSTSFGLSAMSPTK AAVDSLMTIGQSLLQGTLQPPAGPE EPTLAGGGRHPGVAEVKTEMMQVDE VPSQDSPGAAESSISGGMGDKVEER GKEGPGTPTRSSVITSARELHYGRE ESAEQVPPPAEAGQAPTGRPEHPAP PPEKHLGIYSVLPNHKADAVLSMPS SVTSGLHVQPALAVSMDFSTYGGLL PQGFIQRELFSKLGELAVGMKSESR TIGEQCSVCGVELPDNEAVEQHRKL HSGMKTYGCELCGKRFLDSLRLRMH LLAHSAGAKAFVCDQCGAQFSKEDA LETHRQTHTGTDMAVFCLLCGKRFQ AQSALQQHMEVHAGVRSYICSECNR TFPSHTALKRHLRSHTGDHPYECEF CGSCFRDESTLKSHKRIHTGEKPYE CNGCGKKFSLKHQLETHYRVHTGEK PFECKLCHQRSRDYSAMIKHLRTHN GASPYQCTICTEYCPSLSSMQKHMK GHKPEEIPPDWRIEKTYLYLCYVTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
