Recombinant Human ZCCHC17 protein, His-tagged

• Cat.No.: ZCCHC17-3465H
• Product Overview: Recombinant Human ZCCHC17(1-241aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-241 a.a.
• Description: ZCCHC17, also known as pNO40 or PS1D, is a 241 amino acid protein that interacts with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 0.1M NaCl, 0.1mM PMSF
• Molecular Mass: 30.0 kDa (264aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSWVKLIGREMK NDRIKVSLSM KVVNQGTGKD LDPNNVIIEQ EERRRRSFQD YTGQKITLEA VLNTTCKKCG CKGHFAKDCF MQPGGTKYSLMNSGRPE TMENLPALYT IFQGEVAMVT DYGAFIKIPG CRKQGLVHRT HMSSCRVDKP SEIVDVGDKVIPDEEEEKEE AKSAEFEKPD PTRNPSRKRK KEKKKKKHRD RKSSDSDSSD SESDTGKRAR HTSKDSKAAK KKKKKKKHKK KHKE
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ZCCHC17 zinc finger, CCHC domain containing 17 [ Homo sapiens ]
• Official Symbol: ZCCHC17
• Synonyms: ZCCHC17; zinc finger, CCHC domain containing 17; nucleolar protein of 40 kDa; HSPC251; pNO40; PS1D; nucleolar protein 40; pnn-interacting nucleolar protein; putative S1 RNA binding domain protein; putative S1 RNA-binding domain protein; zinc finger CCHC domain-containing protein 17; RP11-266K22.1
• Gene ID: 51538
• mRNA Refseq: NM_016505
• Protein Refseq: NP_057589
• UniProt ID: Q9NP64
• Chromosome Location: 1p35.2
• Function: RNA binding; metal ion binding; zinc ion binding