Recombinant Human ZDHHC12 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ZDHHC12-3276H
• Product Overview: ZDHHC12 MS Standard C13 and N15-labeled recombinant protein (NP_116188) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering. Thereby, indirectly regulates GABAergic synaptic transmission.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 30.6 kDa
• AA Sequence: MAPWALLSPGVLVRTGHTVLTWGIT LVLFLHDTELRQWEEQGELLLPLTF LLLVLGSLLLYLAVSLMDPGYVNVQ PQPQEELKEEQTAMVPPAIPLRRCR YCLVLQPLRARHCRECRRCVRRYDH HCPWMENCVGERNHPLFVVYLALQL VVLLWGLYLAWSGLRFFQPWGLWLR SSGLLFATFLLLSLFSLVASLLLVS HLYLVASNTTTWEFISSHRIAYLRQ RPSNPFDRGLTRNLAHFFCGWPSGS WETLWAEEEEEGSSPAVTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ZDHHC12 zinc finger DHHC-type palmitoyltransferase 12 [ Homo sapiens (human) ]
• Official Symbol: ZDHHC12
• Synonyms: ZDHHC12; zinc finger DHHC-type palmitoyltransferase 12; ZNF400; DHHC-12; palmitoyltransferase ZDHHC12; DHHC domain-containing cysteine-rich protein 12; probable palmitoyltransferase ZDHHC12; zinc finger DHHC domain-containing protein 12; zinc finger DHHC-type containing 12; zinc finger protein 400; EC 2.3.1.225
• Gene ID: 84885
• mRNA Refseq: NM_032799
• Protein Refseq: NP_116188
• UniProt ID: Q96GR4