| Description : |
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
88.8 kDa |
| AA Sequence : |
MNIDDKLEGLFLKCGGIDEMQSSRT MVVMGGVSGQSTVSGELQDSVLQDR SMPHQEILAADEVLQESEMRQQDMI SHDELMVHEETVKNDEEQMETHERL PQGLQYALNVPISVKQEITFTDVSE QLMRDKKQIREPVDLQKKKKRKQRS PAKILTINEDGSLGLKTPKSHVCEH CNAAFRTNYHLQRHVFIHTGEKPFQ CSQCDMRFIQKYLLQRHEKIHTGEK PFRCDECGMRFIQKYHMERHKRTHS GEKPYQCEYCLQYFSRTDRVLKHKR MCHENHDKKLNRCAIKGGLLTSEED SGFSTSPKDNSLPKKKRQKTEKKSS GMDKESALDKSDLKKDKNDYLPLYS SSTKVKDEYMVAEYAVEMPHSSVGG SHLEDASGEIHPPKLVLKKINSKRS LKQPLEQNQTISPLSTYEESKVSKY AFELVDKQALLDSEGNADIDQVDNL QEGPSKPVHSSTNYDDAMQFLKKKR YLQAASNNSREYALNVGTIASQPSV TQAAVASVIDESTTASILESQALNV EIKSNHDKNVIPDEVLQTLLDHYSH KANGQHEISFSVADTEVTSSISINS SEVPEVTPSENVGSSSQASSSDKAN MLQEYSKFLQQALDRTSQNDAYLNS PSLNFVTDNQTLPNQPAFSSIDKQV YATMPINSFRSGMNSPLRTTPDKSH FGLIVGDSQHSFPFSGDETNHASAT STQDFLDQVTSQKKAEAQPVHQAYQ MSSFEQPFRAPYHGSRAGIATQFST ANGQVNLRGPGTSAEFSEFPLVNVN DNRAGMTSSPDATTGQTFGTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
